Cedars-Sinai has established a new Human Microbiome Research Institute that will support investigators studying how the microbiome, the diverse collection of bacteria, fungi and viruses that live in and on the human body, plays a role in health!
The Human Microbiome Research Institute (HMRI) is an innovation hub and coordinating center for Microbiome Research at Cedars-Sinai. The HMRI facilitates exciting human and animal studies from Cedars-Sinai investigators and external collaborators across multiple areas of research including cancer, GI diseases, autoimmunity, metabolism, and early life development. The applicant will have exciting exposure to these broad areas of study with the central uniting theme being that we wish to understand the role of the microbes in and on our bodies in the progression of these diseases.
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Are you ready to be a part of breakthrough research?The Research Associate II (RA II) will be responsible for carrying out molecular, cellular and live animal techniques for external projects submitted to the HMRI. These responsibilities will include, live bacterial cultivation from human and animal tissues, creating bacterial stocks and reviving bacteria as needed, maintain the bacterial culture collection and running in-vitro co-culture experiments, running animal experiments in gnotobiotic mice including gavage of bacteria and bacterial communities. The RA II will also perform PCR and qRT-PCR, ELISAs, perform DNA and RNA extractions, and may learn and take on additional skills such as flow cytometry, FACS sorting, sample preparation for single-cell and single-nuclei sequencing, and advanced microscopy techniques.
Primary Job Duties and Responsibilities:
- Performs a variety of increasingly sophisticated experimental protocols and procedures and assist in the design of new complex or unusual protocols and techniques.
- Keeps accurate and detailed records of experiments and results, and assist in identifying and troubleshooting unexpected results.
- Orders laboratory supplies and supports laboratory operations.
- Maintains lab equipment and related records and may coordinate the use of lab equipment.
- Assists in the operation of specialized equipment, as required by the area of research.
- Orients research laboratory assistants or lower-level research associates and undergraduate student researchers on day-to-day lab operations and routine procedures.
Department-Specific Responsibilities:
- Responsible to carry out molecular, cellular, and live animal techniques for external projects submitted to the HMRI.
- Cultivate live bacteria from human and animal tissues, create bacterial stocks, and revive bacteria as needed.
- Maintain the bacterial culture collection and conduct in-vitro co-culture experiments.
- Perform animal experiments in gnotobiotic mice, including gavage of bacteria and bacterial communities.
- Conduct PCR and qRT-PCR assays.
- Perform ELISAs.
- Perform DNA and RNA extractions.
- Learn and acquire additional skills such as flow cytometry, FACS sorting, sample preparation for single-cell and single-nuclei sequencing, and advanced microscopy.
Education:
Bachelor's Degree in a Science related field is required.
Experience and Skills:
- At least one (1) year of research laboratory experience in the area of research specialization is required.
- Excellent organization good problem-solving skills, detail-oriented, and self-motivated with the ability to multitask.
- Ability to work closely and effectively within a team environment, with the ability to work well independently on specified projects.
- Strong interpersonal skills for interaction with peers and other scientists in the research team as well as with the administrative team within the Center.
Working Title: Research Associate II - Human Microbiome Research Institute
Department: Home Dept - Gastroenterology
Business Entity: Cedars-Sinai Medical Center
Job Category: Academic/Research
Job Specialty: Research Studies/Clinical Trials
Position Type: Full-time
Shift Length: 8 hour shift
Shift Type: Day
Base Pay:$21.26 - $36.14
